TABLE 1.

Clinical characteristics of study patients

CharacteristicValue in the indicated group
Vietnamese patients (n = 107)aUgandan patients (n = 64)a
Patient characteristics
    Median age (yr [range])34 (18-76)34 (18-60)
    No. of males (%)74 (69)38 (59)
    No. of HIV-positive patients (%)1 (0.9)b20 (40)
    No. of unavailable HIV result(s)014
    No. of previous TB episodes (no. of patients [%])
        12 (1.9)54 (84)
        2-307 (11)
        4-503 (5)
    Median duration of cough (days [range]28 (14-336)90 (21-365)
AFB smear grade (no. [%])b0
    Negative53 (65)c
    Scanty (1-9/100 fields)d8 (10)
    1+ (10-99/100 fields)d8 (10)
    2+ (1-10/field)d10 (12)
    3+ (>10/field)d3 (4)
    1+ (1-9/100 fields)e2 (3)
    2+ (1-9/10 fields)e8 (13)
    3+ (1-9/field)e4 (6)
    4+ (>9/field)e50 (78)
Days to positive BACTEC culture (no. [%])f
    <75 (6)54 (84)
    7-2173 (89)8 (13)
    >214 (5)2 (3)
Extent of disease on chest radiograph (no. [%])
    Normal07 (12)
    Minimal21 (26)2 (4)
    Moderate34 (41)9 (16)
    Severe27 (33)38 (68)
Presence of cavities (no. [%])17 (21)35 (63)
No radiograph available (no.)08
  • a Except where indicated otherwise.

  • b Culture-positive subjects only.

  • c Eight subjects classified as AFB negative had one scanty sputum and one smear-negative sputum.

  • d Vietnam study smear definition.

  • e Uganda study smear definition.

  • f Days until growth was flagged by the instrument. BACTEC MGIT 960 was used in the Vietnam study; BACTEC 460 TB was used in the Uganda study.