TABLE 2.

ECVs for anidulafungin, caspofungin, and micafungin and eight species of Candida

SpeciesAntifungal agentNo. of isolates testedMIC (μg/ml)% Isolates with MIC of ≤2 μg/ml
RangeModeECV (%a)
C. albicansAnidulafungin4,2830.007-10.030.12 (99.7)100.0
Caspofungin4,2830.007-0.50.030.12 (99.8)100.0
Micafungin4,2830.007-0.50.0150.03 (97.7)100.0
C. glabrataAnidulafungin1,2360.015-40.060.25 (99.4)99.9
Caspofungin1,2360.015-80.030.12 (98.5)99.8
Micafungin1,2360.007-20.0150.03 (98.2)100.0
C. tropicalisAnidulafungin9960.007-20.030.12 (98.9)100.0
Caspofungin9960.007->80.030.12 (99.4)99.9
Micafungin9960.007-10.0150.12 (99.1)100.0
C. kefyrAnidulafungin610.015-0.120.060.25 (100.0)100.0
Caspofungin610.007-0.030.0150.03 (100.0)100.0
Micafungin610.015-0.060.060.12 (100.0)100.0
C. kruseiAnidulafungin2700.015-0.50.030.12 (99.3)100.0
Caspofungin2700.015-10.060.25 (96.3)100.0
Micafungin2700.015-0.250.060.12 (97.8)100.0
C. lusitaniaeAnidulafungin990.06-10.52 (100)100.0
Caspofungin990.03-10.250.5 (98.0)100.0
Micafungin990.007-10.120.5 (99.0)100.0
C. parapsilosisAnidulafungin1,2380.015-424 (100.0)93.1
Caspofungin1,2380.015-40.251 (98.6)99.9
Micafungin1,2380.015-214 (100)100.0
C. guilliermondiiAnidulafungin880.06-4216 (100.0)92.0
Caspofungin880.03->80.54 (95.5)95.5
Micafungin880.015->80.54 (98.9)98.9
  • a Percentage of isolates for which MIC is less than or equal to the ECV.