TABLE 4.

Description analysis of nucleotide sequence data in all isolates, lineage I isolates, and outbreak isolates of serotype 4b

IsolateGeneNo. of polymorphic sites% of polymorphic sitesNo. of synonymous mutationsNo. of nonsynonymous mutationsdN/dS ratioaπ/siteb
All isolatesprfA388.103360.0150.017
inlB5312.2439150.0800.039
inlC368.3122140.1150.020
dal8419.0570140.0630.067
clpP409.553850.0200.028
lisR6314.15770.0040.031
Lineage I isolatesprfA111.711010.0170.0033
inlB255.772050.1390.023
inlC30.72120.6050.004
dal71.36610.0740.048
clpP153.581320.0670.0005
lisR81.79530.0640.004
Outbreak isolates of serotype 4bprfA30.64210.0580.0015
inlB81.84530.3770.0036
inlC30.72120.5720.0017
dal51.13410.0740.0027
clpP00000
lisR30.67300.0028
  • a The dN/dS ratio was not calculated when the number of nonsynonymous mutations was zero.

  • b Average pairwise nucleotide difference per site.