TABLE 1.

Limits of detection for GXEA, expressed as lowest dilution and lowest nominal concentration detected for each member of the analytical sensitivity panel

SpeciesSerotypeLowest detectable log10 dilutionConcn (TCID50 or LD50/mla)
ACoxsackievirus A2−8NAb
Coxsackievirus A3−45.01
Coxsackievirus A4−6NA
Coxsackievirus A5−712.59
Coxsackievirus A6−712.59
Coxsackievirus A7−83.33*
Coxsackievirus A8−8NA
Coxsackievirus A10−72.81
Coxsackievirus A12−519.95
Coxsackievirus A14−60.1
Coxsackievirus A16−60.02
Enterovirus 71−60.16
BCoxsackievirus A9−820
Coxsackievirus B1−84
Coxsackievirus B2−90.02
Coxsackievirus B3−90.03
Coxsackievirus B4−80.4
Coxsackievirus B5−80.04
Coxsackievirus B6−80.01
Echovirus 1−80.1
Echovirus 2−80.03
Echovirus 3−7200
Echovirus 4−80.00032
Echovirus 5−80.032
Echovirus 6−6200
Echovirus 7−82
Echovirus 9−82
Echovirus 11−740
Echovirus 12−71.58
Echovirus 13−70.01
Echovirus 14−70.0005
Echovirus 15−70.0032
Echovirus 16−70.0005
Echovirus 17−70.05
Echovirus 18−80.0002
Echovirus 19−62.51
Echovirus 20−70.032
Echovirus 21−61
Echovirus 24−70.02
Echovirus 25−60.05
Echovirus 26−60.032
Echovirus 27−70.00032
Echovirus 29−65.01
Echovirus 30−70.005
Echovirus 31−70.0032
Echovirus 32−50.1
Echovirus 33−70.05
Enterovirus 69−80.0002
CCoxsackievirus A13−613.3*
Coxsackievirus A11−60.105*
Coxsackievirus A15−70.0032
Coxsackievirus A17−61.58
Coxsackievirus A18−70.02
Coxsackievirus A19−80.03*
Coxsackievirus A20−70.0019
Coxsackievirus A21−70.03
Coxsackievirus A22−70.02
Coxsackievirus A24−70.1
DEnterovirus 68−4200
Enterovirus 70−72
PoliovirusPoliovirus 1−82
Poliovirus 2−80.4
Poliovirus 3−820
  • a *, LD50/ml.

  • b NA, not available.