TABLE 4.

Comparison of clinical characteristics of patients with CoV-HKU1, HCoV-NL63, HCoV-OC43, and HCoV-229E infections

ParameterValue for patients infected with:
CoV-HKU1HCoV-NL63HCoV-OC43HCoV-229E
Total no. of patients13175313
Male-to-female ratio8:58:928:251:3
Age
    Range19 mo-87 yr6 mo-86 yr1 mo-88 yr2 yr-75 yr
    Median (yr)4298.5
Duration of fever (days)
    Range1-41-71-81-4
    Median1112.5
Duration of hospitalization (days)
    Range2-71-91-203-14
    Median3333
No. (%) of patients with underlying diseases8 (62)10 (59)34 (64)2 (50)
No. (%) of patients with diagnosis ofa:
    URTIc11 (85)12 (71)41 (77)2 (50)
    Asthma/COPD exacerbationc1 (8)2 (12)4 (8)0 (0)
    Acute bronchiolitis1 (8)1 (6)3 (6)0 (0)
    Pneumonia1 (8)3 (18)8 (15)2 (50)
    Croup0 (0)2 (12)0 (0)0 (0)
    Febrile convulsion5 (38)b3 (18)3 (6)b0 (0)
    Breakthrough seizure2 (15)b1 (6)0 (0)b0 (0)
    Aseptic meningitis0 (0)0 (0)1 (2)0 (0)
    Kawasaki disease0 (0)0 (0)1 (2)0 (0)
No. (%) of patients who died0 (0)0 (0)1 (2)0 (0)
  • a Percentages add up to >100% because some patients had more than one diagnosis.

  • b P < 0.05.

  • c URTI, upper respiratory tract infection; COPD, chronic obstructive pulmonary disease.