TABLE 3.

Inhibition zone diameters obtained on MH agar by the disk diffusion method for two QC isolatesa

QC isolateb and antifungal agentZone range in millimeters (% agreement) at:
24 h48 h72 h
Paecilomyces variotii ATCC 3630
    Itra25-31 (99)23-31 (94)24-31 (97)
    Posa35-46 (100)37-45 (97)37-44 (97)
    Vori-140-53 (94)41-53 (94)41-53 (100)
    Vori-1056-64 (97)60-71 (86)61-73 (89)
    Cas-BBL23-29 (100)23-30 (97)24-30 (97)
    Cas-Oxoid23-34 (100)23-34 (97)22-33 (89)
    Amb13-22 (94)9-19 (83)10-19 (89)
Candida krusei ATCC 6258
    Itra21-30 (100)20-29 (100)20-28 (100)
    Posa31-43 (97)30-41 (97)30-41 (97)
    Vori-129-38 (100)25-35 (100)24-36 (97)
    Vori-1047-59 (92)46-60 (97)53-61 (92)
    Cas-BBL14-24 (100)18-27 (97)17-25 (97)
    Cas-Oxoid21-29 (100)21-30 (100)21-32 (100)
    Amb19-27 (100)15-25 (97)13-25 (97)
  • a Tests were performed 5 to 16 times for each isolate in each of the five laboratories for each disk and incubation time on MH agar.

  • b Itra, itraconazole 10-μg disk; Posa, posaconazole 5-μg disk; Cas-BBL and Cas-Oxoid, caspofungin 5-μg disks from two sources; Vori-1 and Vori-10, voriconazole 1-μg and 10-μg disks, respectively; Amb, amphotericin B 10-μg disk.