TABLE 1.

Epidemiological characteristics and outcomes of 294 patients with candidemia by type of fungal isolate

Variable (no. of patients [%])aPatients infected with:Pb
Candida albicans (n = 168)Non-C. albicans Candida species (n = 126)
Age (yr) (mean ± SD)64.9 ± 15.465.1 ± 13.70.90
Male sex74 (44)50 (39.6)0.45
Hospital-acquired candidemia154 (91.6)108 (85.7)0.10
Duration of hospitalization (no. of days) (mean ± SD)c47.7 ± 38.250.1 ± 42.60.60
Diabetes32 (19)26 (20.6)0.73
Liver disease16 (9.5)14 (11.1)0.65
Solid-organ cancer76 (45.2)42 (33.3)0.03
Hematological malignancy12 (7.1)14 (11.1)0.23
Neutropeniad10 (5.9)8 (6.3)0.88
Immunosuppressive therapy82 (48.8)38 (30.1)0.001
Surgical admission100 (59.5)62 (49.2)0.07
In the ICU at diagnosis57 (33.9)45 (35.7)0.75
Indwelling urinary catheter136 (80.9)90 (71.4)0.05
CVC120 (71.4)93 (73.8)0.65
TPN72 (42.8)66 (52.3)0.10
CVC-related candidemia30 (17.8)30 (23.8)0.21
Mortality rate97 (57.7)57 (45.2)0.03
  • a Values are presented as the number (percentage) of patients with the specified characteristic, unless otherwise indicated.

  • b P value comparing the value for patients infected with C. albicans to the value for patients infected with non-C. albicans Candida species.

  • c For patients transferred from another hospital, the duration of hospitalization was calculated by the date of the first hospital admission.

  • d White blood cell count of less than 0.5 × 109 cells/liter.