TABLE 2.

Reproducibility of inhibition zone diameters, in millimeters, obtained by the disk diffusion method with five antifungal agents for 72 mold isolates at two of the five centersa

Antifungal agent and mediumb% within 2-SD zone at:
24 h48 h72 h
Itra
    MH969188
    MGM878282
Posa
    MH979592
    MGM969694
Vori-1
    MH979493
    MGM979590
Vori-10
    MH929392
    MGM929392
Cas-BBL
    MH1009695
    MGM969487
Cas-Oxoid
    MH1009797
    MGM10010097
Amb
    MH959595
    MGM1009591
  • a Percentages of replicate zone diameters within 2 standard deviations of the mean; each of the 72 isolates was tested on 3 different days in two of the five laboratories with each antifungal agent. Inhibition zone diameters, in millimeters, on both MH and MGM agar were read at 16 to 24, 48, and 72 h.

  • b Itra, itraconazole 10-μg disk; Posa, posaconazole 5-μg disk; Cas-BBL and Cas-Oxoid, caspofungin 5-μg disks from two sources; Vori-1 and Vori-10, voriconazole 1-μg and 10-μg disks, respectively; Amb, amphotericin B 10-μg disk.