TABLE 4.

Kinetics of PUUV RNA and antibodies in sera of patients clinically diagnosed with suspected NE

Patient/day after disease outbreakPUUV RNA detected by real-time RT-PCR (copies/ml)PUUV IgM titerPUUV IgG titer
A/3586,4456480
A/525,281128320
A/71,285256NDb
B/3ND+a640
B/48,0001281,280
B/52,0001282,560
B/61,3001282,560
B/72,0001282,560
B/86002562,560
B/902652,560
B/1002562,560
C/3196,000NDND
C/483,00016320
C/511,20064640
C/6064640
D/41,800,0008<40
D/7450,00032<40
E/36,0008<40
E/443064160
E/540NDND
E/630128640
E/7302561,280
E/830256640
F/357,0001640
F/902562560
  • a IgM was diluted 1:16 and scored as positive (+) by IF.

  • b ND, not determined.