TABLE 1.

Clinical summary for 15 patients with C. glabrata fungemia in this study

Patient no.Age (yr)/sexAdmission diagnosisNo. of positive cultures (days of culture)aAntifungal therapy (days of treatment)bOutcome
144/FPanperitonitis due to multiple leakage2 (0, 28)NoneImproved
240/FPanperitonitis due to duodenal rupture3 (0, 1, 2)NoneImproved
385/FRenal failure, Escherichia coli bacteremia2 (0, 1)NoneNot improved
461/MLiver cirrhosis, gastrointestinal bleeding5 (0, 1, 4, 6, 7)NoneNot improved
53/FAcute lymphocytic leukemia2 (0, 1)NoneNot improved
651/FCerebral hemorrhage2 (0, 1)NoneNot improved
733/FRenal transplantation3 (0, 2, 36)Flu 100 mg (4-11), Itra 100 mg (12-15), Flu 300 mg (35), AmB 50 mg (45-54, 62)Not improved
840/FPeritoneal carcinomatosis4 (0, 1, 8, 22)Flu 400 mg (7-10), Flu 400 mg (24-38)Improved
953/MPanperitonitis due to ileal injury3 (0, 1, 23)AmB 50 mg (7-33), Flu 400 mg (24-25)Improved
1062/MSquamous cell carcinoma of lung4 (0, 4, 8)Flu 400 mg (2-11)Not improved
1155/MDiabetes, liver cirrhosis, gastrointestinal bleeding2 (0, 1)Flu 200 mg (−19 to 4)cNot improved
1271/MAcute drug intoxication, pneumonia3 (0, 4, 7)AmB 50 mg (9-37)Improved
1369/MEpidural abscess2 (0, 1)Flu 400 mg (3-10), AmB 100 mg (10-13)Improved
1446/FPanperitonitis due to ileal perforation3 (0, 12, 24)AmB 50 mg (16-49)Improved
1516/FRenal transplantation2 (0, 11)Flu 100 mg (8-21)Improved
  • a The numbers in parentheses indicate the days on which positive blood cultures were made; for each patient, day 0 represents the day that the first positive blood culture was made, and the day(s) on which subsequent positive cultures were made are represented by the subsequent numbers.

  • b The numbers in parentheses indicate the day(s) after positive blood culture that the corresponding treatment was given. AmB, amphotericin B; Flu, fluconazole; Itra, itraconazole.

  • c Fungemia occurred during antifungal therapy (for the treatment of C. albicans candidemia) in patient 11.