TABLE 3.

Correlation between real-time RT-PCR and IgM for detection of PUUV infection in patients from northern Sweden clinically diagnosed with suspected NEa

PCR resultNo. IgM positiveNo. IgM negativeTotal
Positive33134
Negative14849
Total344983
  • a Using IgM as the reference, real-time RT-PCR had a clinical specificity of 98% (CI, 93%, 99%), a clinical sensitivity of 97% (CI, 90%, 99%), a PPV of 97% (CI, 90%, 99%), and an NPV of 98% (CI, 93%, 99%). The statistical analysis was calculated using standard formulas with 95% CI.