TABLE 3.

PCR assay results for 216 subjects, using Nugent criteria to define BVa

BacteriumSensitivity (%) (95% CI)Specificity (%) (95% CI)OR (95% CI)
BVAB131.5 (22.0-42.9)97.2 (93.0-98.9)16.0 (5.3-48.5)
BVAB280.8 (70.3-88.2)96.5 (92.1-98.5)116 (40.1-338)
BVAB326.0 (17.3-37.1)97.2 (93.0-98.9)12.2 (4.0-37.6)
G. vaginalis 97.3 (90.6-99.3)45.5 (37.5-53.6)29.6 (7.0-125)
Atopobium spp.95.9 (88.6-98.6)84.6 (77.8-89.6)128 (37.1-444)
Eggerthella-like bacterium89.0 (79.8-94.3)94.4 (89.4-97.1)137 (49.3-382)
Leptotrichia spp.73.9 (69.2-82.7)93.7 (88.5-96.7)42.3 (18.0-99.4)
Megasphaera phylotype 194.5 (86.7-97.9)94.4 (89.4-97.1)291 (84.7-1,000)
Megasphaera phylotype 26.9 (3.0-15.1)100 (97.4-100)Infinity
Either Megasphaera sp.95.9 (88.6-98.6)94.4 (89.4-97.1)394 (101-1,531)
BVAB-TM724.7 (16.2-35.6)99.3 (92.6-99.9)46.5 (6.1-357)
M. curtisii 49.3 (38.2-60.5)93.0 (87.6-96.2)12.9 (5.9-28.5)
M. mulieris 16.4 (9.7-26.6)98.6 (95.0-99.6)13.9 (3.0-63.8)
Either Mobiluncus sp.54.8 (43.4-65.7)91.6 (85.9-95.1)13.2 (6.3-28.0)
Peptoniphilus sp. type 178.1 (67.3-86.0)67.1 (59.1-74.3)7.3 (3.8-14.0)
Peptoniphilus lacrimalis 61.6 (50.2-72.0)84.6 (77.8-89.6)8.8 (4.6-17.0)
Either Peptoniphilus sp.82.2 (71.9-89.3)62.9 (54.8-70.4)7.8 (3.9-15.6)
Prevotella G150.7 (39.5-61.8)97.2 (93.0-98.9)35.7 (12.0-107)
L. crispatus 8.2 (3.8-16.8)6.3 (3.4-11.5)0.006 (0.002-0.018)
L. iners 94.5 (86.7-97.9)11.9 (7.6-18.2)2.3 (0.75-7.2)
Either BVAB1 or BVAB280.8 (70.3-88.2)96.5 (92.1-98.5)116 (40.1-338)
Either BVAB1 or BVAB335.6 (25.6-47.1)96.5 (92.1-98.5)15.3 (5.6-42.0)
Either BVAB2 or BVAB382.2 (71.9-89.3)96.5 (92.1-98.5)127 (43.5-373)
Either BVAB1, -2, or -382.9 (71.9-89.3)96.5 (92.1-98.5)127 (43.5-373)
Either Megasphaera phylotype 1 or BVAB295.9 (88.6-98.6)93.7 (88.5-96.7)347 (91.1-1,324)
  • a The analysis consisted of 73 subjects with BV and 143 subjects without BV.