Variation in dalbavancin MIC ratios for clinical strains tested without or with P-80
Organism (no. of isolates tested) | No. of observationsa at an MIC ratio (without P-80/with P-80) of: | |||||
---|---|---|---|---|---|---|
0.25 | 0.5 | 1 | 2 | 4 | 8 | |
S. aureus (35) | - | - | 1 | 3 | 28 | 3 |
Coagulase-negative staphylococci (20) | - | - | 1 | 11 | 6 | 2 |
Enterococcus spp. (10) | - | 1 | 2 | 3 | 4 | - |
Beta-hemolytic streptococci (15) | - | - | 10 | 4 | 1 | - |
Viridans group streptococci (10) | - | 1 | 5 | 4 | - | - |
S. pneumoniae (10) | - | - | 8 | 2 | - | - |
Total (100) | -‡ | 2†‡ | 27*†‡ | 27†‡ | 39‡ | 5 |
↵a -, No observations. *, 27% identical results; †, 56% ± 1 log2 dilution step; ‡, 95% ± 2 log2 dilution steps.