TABLE 3.

Pairwise associations of selected sJPX probes and lic2B among a panel of 121 middle ear NT H. influenzae isolates and 137 NT H. influenzae isolates from the throats of healthy childrena

Genetic region and virulence factor pairsNORLower 95% CIUpper 95% CIP valueGenetic region and virulence factor pairsNORLower 95% CIUpper 95% CIP value
sPCR fragments    sJPX132-sJPX17625857.57.5440<0.0001*
    sJPX084-sJPX101s25820579.9<0.0001**    sJPX147-ssJPX1612583.30.812.60.1027**
    sJPX084-sJPX12025838.45.2284.7<0.0001    sJPX147-sJPX16325817.55.754.2<0.0001**
    sJPX084-sJPX1242589931.4312.5<0.0001    sJPX147-sJPX17625873.920.2270.2<0.0001**
    sJPX084-sJPX13225816822.41262.5<0.0001    sJPX161-sJPX16325820826.41647.6<0.0001*
    sJPX084-sJPX14725818.35.956.7<0.0001**    sJPX161-sJPX1762584.31.314.60.0332**
    sJPX084-sJPX16125822127.91751.7<0.0001*    sJPX163-sJPX17625847.212.7175.2<.0001**
    sJPX084-sJPX1632587920484.5129478<0.0001*
    sJPX084-sJPX17625849.513.3184.5<0.0001**lic2B
    sJPX101s-sJPX1202583.80.817.90.1183**    lic2B-sJPX08425827.63.7205.3<0.0001
    sJPX101s-sJPX124258133.351.10.0001**    lic2B-sJPX101s2587.10.955.40.0.331*
    sJPX101s-sJPX132258283.5223<0.0001    lic2B-sJPX1202587.94.514<0.0001
    sJPX101s-sJPX1472581.50.212.90.5126**    lic2B-sJPX1242587.12.718.7<0.0001
    sJPX101s-sJPX1612585.41.322.40.0385**    lic2B-sJPX1322582.61.44.90.0015
    sJPX101s-sJPX16325833.87164.3<0.0001**    lic2B-sJPX1402582.41.440.0008
    sJPX101s-sJPX1762589.52.536.40.0041**    lic2B-sJPX1472584.5120.40.0324
    sJPX120-sJPX1242584.11.98.6<0.0001    lic2B-sJPX16125812.11.6920.0025
    sJPX120-sJPX1322583.31.85.9<0.0001    lic2B-sJPX16325828.63.9212.5<0.0001
    sJPX120-sJPX1472586.11.427.60.0077    lic2B-sJPX17625812.11.6920.0007*
    sJPX120-sJPX16125816.42.2124.90.0003
    sJPX120-sJPX16325839.85.4295.1<0.0001hmwA (sJPX140)
    sJPX120-sJPX1762584.41.215.50.0135    sJPX140-sJPX08425840.55.5300.6<0.0001*
    sJPX124-sJPX13225827.81264.7<0.0001    sJPX140-sJPX10125891.171.40.0127*
    sJPX124-sJPX147258246.588.4<0.0001**    sJPX140-sJPX1202582.61.64.30.0002
    sJPX124-sJPX16125832.28.9116.3<0.0001**    sJPX140-sJPX124258195.763<0.0001
    sJPX124-sJPX163258108.434.2343.7<0.0001    sJPX140-sJPX13225812817.4942.9<0.0001
    sJPX124-sJPX17625829.38.1106.4<0.0001**    sJPX140-sJPX1472583.91.113.90.0273
    sJPX132-sJPX1472588.52.727.40.0001**    sJPX140-sJPX16125817.32.3131.40.0002*
    sJPX132-sJPX16125857.57.5440<0.0001    sJPX140-sJPX163258425.7311.8<0.0001*
    sJPX132-sJPX163258177.223.61331.6<0.0001    sJPX140-sJPX17625835.22.2129.20.0003*
  • a Boldface indicates significance with a P value of <0.0008, obtained by using the Bonferroni correction of multiple comparisons. **, P value determined by Fisher's exact test; N, number of isolates analyzed for each probe pair; *, use of a correction of 1 for cells with a frequency of zero.