TABLE 3.

Comparison on a per-analyte basis of the results of the PLx-RVP assay, version 1, with those obtained using the WSLH testing algorithm for all 687 samples

VirusNo. of specimensaSensitivity (%) (95% CI)bSpecificity (%) (95% CI)b
W+ P+W P+W+ PW P
Influenza A virus29821037796.8 (94.1-98.2)99.2 (98.1-99.9)
Influenza B virus7407154251 (43.0-59.0)100 (99.3-100)
RSV125766363.2 (41.0-80.9)99.3 (98.3-99.7)
PIV91467369.2 (42.4-87.3)99.9 (99.2-100)
Ad1260669100 (75.7-100)99.1 (98.1-99.6)
Rhinovirus6150666100 (61.0-100)97.8 (96.4-98.7)
  • a W+ and W, positive and negative, respectively, by the WSLH testing algorithm; P+ and P, positive and negative, respectively, by the PLx-RVP test.

  • b Sensitivity and specificity calculations were based on “true positives” and “true negatives,” defined as specimens giving positive or negative results, respectively, by the WSLH testing algorithm. Sensitivity, specificity, and confidence intervals (CI) were calculated according to CLSI recommendations (7a).