TABLE 1.

Clinical characteristics and results of IS900 PCR testing for Mycobacterium avium subsp. paratuberculosis in participants

Group and sexaAge (yr)History (yr)IBS typebDisease locationDisease activityDrug(s)IS900 PCR resultcReason for endoscopy
IBS
    F558MNoneNEG
    F592CNoneNEG
    F252DNoneNEG
    F532CPrednisoneA1, A2, D2
    F475CPrednisoneT1, T2, A1, A2, D1,d D2
    F701DNoneNEG
    F332CPrednisoneA2
    F564CNoneNEG
    F699CNoneT2, A1, A2
    M502CNoneD2
    F643CNoneD1
    M581DNoneA1, A2, D1, D2
    F382MNoneT1, D1, D2
    F485CNoneT1, T2, A2, D1, D2
    F3615DNoneA1, A2
    F647CNoneT1, T2, A1, D1
    F681CNoneD1
    F692DNoneT2
    F504CNoneT2
    M452DNoneD2
Non-IBS/IBD
    M67NEGScreening
    M59NEGScreening
    F63NEGTumor markers
    M77NEGAbdominal pain
    M45NEGScreening
    F47NEGFollow-up
    M60A1, A2,d D1, D2Follow-up
    F45NEGAbdominal pain
    F67NEGFollow-up
    M54A1Screening
    M64NEGScreening
    M67NEGScreening
    F46NEGAbdominal pain
    M51T1, T2Screening
    M59NEGTumor markers
    M67NEGScreening
    M74NEGScreening
    F49NEGScreening
    M79NEGScreening
    F67NEGScreening
Crohn's disease
    M583Ileum/colonInactiveMesalazineD1
    M143ColonActiveMesalazineT1, T2, A2e
    F541Ileum/colonActiveNoneA1, D2e
    F270.5Ileum/colonActiveNoneT1, T2e
    M3110IleumActiveOlsalazineT1, A1e
    F6115IleumInactiveMesalazineT1,d D2
    M304IleumInactiveMesalazineNEGe
    F510.08Ileum/colonActiveNoneT1, T2e
    M350.5IleuminactiveNoneT2, A2
    M142ColonActiveMesalazine, rifampin, clarithromycinNEGe
    F250.25IleumActiveMesalazineA1e
    F186IleumActiveAzathioprine, mesalazineA1, D1e
    M228IleumActiveMesalazineT2e
    F280.25IleumActiveMesalazineT1, A1e
    F110.08IleumActiveNoneT2e
    F719IleumActiveMesalazineA2
    F5110Duodenum/ileum/colonActivePrednisoneD1, D2e
    F272IleumActiveMesalazineT2, A2, D2e
    F236IleumActivePrednisoneT1
    M466IleumActiveMesalazine, rifampin, clarithromycinNEG
    F358ColonActiveMesalazine, prednisoneA2, D2e
    F4020IleumActiveMesalazineA1, A2
    M265Duodenum/ileumActiveMesalazine, budesonideT1, T2, A1, A2, D1, D2e
  • a M, male; F, female.

  • b D, diarrhea; C, constipation; M, mixed type.

  • c T, terminal ileum; A, ascending colon; D, descending colon; NEG, negative.

  • d A C-to-T transition was identified at position 247 in this biopsy specimen.

  • e Granuloma positive.