TABLE 3.

Clinical symptoms and IgM serologic results of patients in the IgM panels

Sample no./sex/age (yr)IgM IFA titeraResultb by:Symptom(s)
Focus (IV)PANBIO (IV)CDCPRNT (titer)
20/F/72162.371.32Pos NDcHeadache, fever, meningitis, diarrhea
22/F/31163.091.14PosND Headache, fever, meningitis, encephalitis, diarrhea, coma
24/M/29163.671.47PosND Headache, fever, diarrhea, vomiting
25/M/672563.291.49PosND Confusion, weakness, renal insufficiency, myoglobinuria
26/M/76642.651.48PosND Fever, anorexia
30/M/26322.031.16Pos640Headache, fever, meningitis
33/F/362562.841.25PosND Headache, fever
36/F/44643.011.36PosND Headache, fever, myalgia
91/F/551283.301.78PosND Headache, fever, fatigue, joint pain
92/F/80643.201.59PosND Fever
95/M/701283.071.29PosND Headache, fever, meningitis, encephalitis
108/F/21641.540.89PosND Nausea, vomiting
124/M/671283.351.42Pos5,120Headache, fever
125/F/651,0243.381.67NDND Fever, altered mental status, hematemesis
126/M/69322.471.26Pos40Headache, fever, meningitis, diplopia, ophthalmoplegia
127/F/62<160.530.22NegND Headache, anorexia
128/F/711283.711.51Pos160Fever
129/F/71320.180.63NegND Fever, confusion, tremor, hypotension
130/M/55<160.480.23NegND Pneumonia, septic shock
131/M/285123.441.63NDND Headache, fever
132/F/342563.211.79Pos320Headache, fever
133/F/49641.801.20Pos40Headache, fever, confusion
134/M/69<160.070.16NegND Headache
135/F/752563.521.60Pos320Fever, facial weakness progressing to flaccid paralysis on left side
136/M/261281.721.43Pos320Headache, fever, meningitis, neck stiffness
137/F/unkd643.802.09PosND Fever, altered mental status, hematemesis
138/F/43643.041.39Pos20Headache
139/M/57642.991.49Pos40Fever, rash, myalgias
140/F/43<160.901.02Pos40Headache, encephalitis, nausea, vomiting, diarrhea, Guillain-Barré-type symptoms
141/F/931,0243.211.56Pos80Fever, fatigue
143/M/782563.551.36Pos2,560Altered mental status, respiratory failure
144/F/52<160.190.39Neg20Headache, fever
145/M/591,0242.911.59Pos80Headache, fever, meningitis, hypotension, chills
146/M/501283.111.57Pos320Fever, anorexia, myalgia
147/M/465122.651.60Pos640Fever, altered mental status, hematemesis
148/F/502562.951.39Pos80Headache, fever, quadraparesis
149/M/685123.161.40Pos160Fever, weakness, respiratory distress
150/F/75<160.540.30Pos2,560Headache, diplopia
152/F/53643.471.58Pos40Meningitis
177/F/425123.611.62PosND Headache, fever, anorexia, fatigue, maculopapular skin rash
188/F/751,0244.091.46Pos160Fever, seizures, coma
  • a IFA titers are shown as reciprocal values. IFA reference interval, <16.

  • b Focus, PANBIO, and CDC, Focus, PANBIO, and CDC IgM antibody-capture ELISAs, respectively. ELISA and PRNT reference intervals, <0.90 and <10, respectively. IV, index value.

  • c ND, not done.

  • d unk, unknown.