TABLE 1.

Antimicrobial susceptibility profile of the K. pneumoniae strain KPBr-1 carrying the blaIMP-1 and blaCTX-M genes

Antimicrobial agentMIC (μg/ml)
Vitek systemEtestAgar dilution method
Piperacillin>64
Piperacillin-tazobactam>64
AZT>16, ESBLc12
Cefoxitin>16>256>512
Ceftriaxone>32, ESBL>256512
Cefotaxime>32, ESBL512
Cefotaxime-clavulanic acid512a
Cefotaxime-EDTA256b
Ceftazidime>16>256256
Ceftazidime-clavulanic acid>32->4.0256a
Ceftazidime-EDTA2b
Cefpodoxime>1
Cefepime>16>256
Ciprofloxacin>2>32
IMP>8>32128
IMP-clavulanic acid128a
IMP-EDTA1b
  • a Clavulanic acid was tested at a fixed concentration of 4 μg/ml.

  • b EDTA was tested at a fixed concentration of 320 μg/ml.

  • c ESBL, carrying an ESBL phenotype.