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Journal of Clinical Microbiology
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Antiviral Agents

  • Amino Acid Substitutions Associated with Treatment Failure for Hepatitis C Virus Infection
    Virology
    Amino Acid Substitutions Associated with Treatment Failure for Hepatitis C Virus Infection

    Despite the high virological response rates achieved with current directly acting antiviral agents (DAAs) against hepatitis C virus (HCV), around 2% to 5% of treated patients do not achieve a sustained viral response. The identification of amino acid substitutions associated with treatment failure requires analytical designs, such as subtype-specific ultradeep sequencing (UDS) methods, for HCV characterization and patient management....

    María Eugenia Soria, Carlos García-Crespo, Brenda Martínez-González, Lucía Vázquez-Sirvent, Rebeca Lobo-Vega, Ana Isabel de Ávila, Isabel Gallego, Qian Chen, Damir García-Cehic, Meritxell Llorens-Revull, Carlos Briones, Jordi Gómez, Cristina Ferrer-Orta, Nuria Verdaguer, Josep Gregori, Francisco Rodríguez-Frías, María Buti, Juan Ignacio Esteban, Esteban Domingo, Josep Quer, Celia Perales
  • Virology
    Differentiated Levels of Ganciclovir Resistance Conferred by Mutations at Codons 591 to 603 of the Cytomegalovirus UL97 Kinase Gene
    Sunwen Chou, Ronald J. Ercolani, Adam L. Vanarsdall
  • Virology
    Hepatitis B Virus (HBV) Subgenotypes C2 and B2 Differ in Lamivudine- and Adefovir-Resistance-Associated Mutational Patterns in HBV-Infected Chinese Patients
    Xiaodong Li, Lin Wang, Yanwei Zhong, Vincent Wai-Sun Wong, Zhihui Xu, Yan Liu, Qinghong Li, Shaojie Xin, Jingmin Zhao, Dongping Xu
  • CASE REPORTS
    Detection of Oseltamivir Resistance during Treatment of 2009 H1N1 Influenza Virus Infection in Immunocompromised Patients: Utility of Cycle Threshold Values of Qualitative Real-Time Reverse Transcriptase PCR
    Tejal Mehta, Eric McGrath, Suchitha Bheemreddy, Hossein Salimnia, Nahed Abdel-Haq, Jocelyn Y. Ang, Lawrence Lum, Pranatharthi Chandrasekar, George J. Alangaden
  • Virology
    Use of Acyclovir for Suppression of Human Immunodeficiency Virus Infection Is Not Associated with Genotypic Evidence of Herpes Simplex Virus Type 2 Resistance to Acyclovir: Analysis of Specimens from Three Phase III Trials
    Deborah Watson-Jones, Anna Wald, Connie Celum, Jairam Lingappa, Helen A. Weiss, John Changalucha, Kathy Baisley, Clare Tanton, Richard J. Hayes, Joshua O. Marshak, Rula Green Gladden, David M. Koelle
  • Virology
    Peptide Nucleic Acid Array for Detection of Point Mutations in Hepatitis B Virus Associated with Antiviral Resistance
    Hyunjung Jang, Jihyun Kim, Jae-jin Choi, Yeojin Son, Heekyung Park
  • Free
    LETTERS TO THE EDITOR
    Rapid Genotypic Assay for Detection of Oseltamivir-Resistant Influenza A (H1N1) Viruses
    Mami Hata, Seidai Tanaka, Yoshihiro Yasui, Noriko Fujiwara, Shinichi Kobayashi, Hiroko Minagawa
  • Free
    Virology
    Genetic Makeup of Amantadine-Resistant and Oseltamivir-Resistant Human Influenza A/H1N1 Viruses
    Hassan Zaraket, Reiko Saito, Yasushi Suzuki, Tatiana Baranovich, Clyde Dapat, Isolde Caperig-Dapat, Hiroshi Suzuki
  • Virology
    Selection and Counterselection of the rtI233V Adefovir Resistance Mutation during Antiviral Therapy
    Oliver Schildgen, Cynthia Olotu, Anneke Funk, Bernhard Zöllner, Martin Helm, Jürgen Kurt Rockstroh, Hüseyin Sirma
  • Free
    Virology
    Evidence for Persistence of and Antiviral Resistance and Reassortment Events in Seasonal Influenza Virus Strains Circulating in Cambodia
    Mathieu Fourment, Sek Mardy, Mey Channa, Philippe Buchy

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