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automation

  • Open Access
    Performance Characteristics of a High-Throughput Automated Transcription-Mediated Amplification Test for SARS-CoV-2 Detection
    Virology
    Performance Characteristics of a High-Throughput Automated Transcription-Mediated Amplification Test for SARS-CoV-2 Detection

    The COVID-19 pandemic caused by the new SARS-CoV-2 coronavirus has imposed severe challenges on laboratories in their effort to achieve sufficient diagnostic testing capability for identifying infected individuals. In this study, we report the analytical and clinical performance characteristics of a new, high-throughput, fully automated nucleic acid amplification test system for the detection of SARS-CoV-2. The assay utilizes target...

    Jimmykim Pham, Sarah Meyer, Catherine Nguyen, Analee Williams, Melissa Hunsicker, Ian McHardy, Inessa Gendlina, D. Yitzchak Goldstein, Amy S. Fox, Angela Hudson, Paul Darby, Paul Hovey, Jose Morales, James Mitchell, Karen Harrington, Mehrdad Majlessi, Joshua Moberly, Ankur Shah, Andrew Worlock, Marion Walcher, Barbara Eaton, Damon Getman, Craig Clark
  • Free
    Evaluation of the WASPLab Segregation Software To Automatically Analyze Urine Cultures Using Routine Blood and MacConkey Agars
    Bacteriology
    Evaluation of the WASPLab Segregation Software To Automatically Analyze Urine Cultures Using Routine Blood and MacConkey Agars

    Automation of the clinical microbiology laboratory has become more prominent as laboratories face higher specimen volumes and understaffing and are becoming more consolidated. One recent advancement is the use of digital image analysis to rapidly distinguish between chromogenic growth for screening bacterial cultures. In this study, colony segregation software developed by Copan (Brescia, Italy) was evaluated to distinguish between...

    Matthew L. Faron, Blake W. Buchan, Ryan F. Relich, James Clark, Nathan A. Ledeboer
  • Open Access
    Evaluation of WASPLab Software To Automatically Read chromID CPS Elite Agar for Reporting of Urine Cultures
    Bacteriology
    Evaluation of WASPLab Software To Automatically Read chromID CPS Elite Agar for Reporting of Urine Cultures

    Urine cultures are among the most common specimens received by clinical laboratories and generate a major share of the laboratory workload. Chromogenic agar can expedite culture results, but technologist review is still needed. In this study, we evaluated the ability of the WASPLab software to interpret urine specimens plated onto chromID CPS Elite (CPSE) agar. Urine specimens submitted for bacterial culture were plated onto CPSE agar...

    Matthew L. Faron, Blake W. Buchan, Hasan Samra, Nathan A. Ledeboer
  • Virology
    Evaluation of Performance Characteristics of Panther Fusion Assays for Detection of Respiratory Viruses from Nasopharyngeal and Lower Respiratory Tract Specimens

    Accurate and rapid diagnosis is needed for timely intervention and clinical management of acute respiratory infections. This study evaluated performance characteristics of the Panther Fusion assay for the detection of influenza A virus (Flu A), influenza B virus (Flu B), respiratory syncytial virus (RSV), parainfluenza viruses 1 to 3 (Para 1 to 3), human metapneumovirus (hMPV), rhinovirus (RV), and adenovirus (Adeno) targets in...

    Soya S. Sam, Angela M. Caliendo, Jessica Ingersoll, Deborah Abdul-Ali, Charles E. Hill, Colleen S. Kraft
  • Virology
    Multicenter Clinical Evaluation of the Alere i Respiratory Syncytial Virus Isothermal Nucleic Acid Amplification Assay
    Ferdaus Hassan, Lindsay M. Hays, Aleta Bonner, Bradley J. Bradford, Ruffin Franklin, Phyllis Hendry, Jed Kaminetsky, Michael Vaughn, Kristin Cieslak, Mary E. Moffatt, Rangaraj Selvarangan
  • Bacteriology
    Comparison of BD Phoenix, Vitek 2, and MicroScan Automated Systems for Detection and Inference of Mechanisms Responsible for Carbapenem Resistance in Enterobacteriaceae
    Neil Woodford, Anne T. Eastaway, Michael Ford, Alistair Leanord, Chloe Keane, Reinhard M. Quayle, Jane A. Steer, Jiancheng Zhang, David M. Livermore
  • Virology
    New Automated Hepatitis C Virus (HCV) Core Antigen Assay as an Alternative to Real-Time PCR for HCV RNA Quantification
    Yongjung Park, Jong-Han Lee, Beom Seok Kim, Do Young Kim, Kwang-Hyub Han, Hyon-Suk Kim
  • Bacteriology
    Clinical Utility of an Automated Instrument for Gram Staining Single Slides
    Ellen Jo Baron, Samantha Mix, Wais Moradi
  • Virology
    Comparative Evaluation of a Commercially Available Automated System for Extraction of Viral DNA from Whole Blood: Application to Monitoring of Epstein-Barr Virus and Cytomegalovirus Load
    Sylvie Pillet, Thomas Bourlet, Bruno Pozzetto
  • Virology
    Ultra-High-Throughput, Automated Nucleic Acid Detection of Human Immunodeficiency Virus (HIV) for Infant Infection Diagnosis Using the Gen-Probe Aptima HIV-1 Screening Assay
    Wendy S. Stevens, Lara Noble, Leigh Berrie, Somaya Sarang, Lesley E. Scott

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