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avibactam

  • A Selective Culture Medium for Screening Ceftazidime-Avibactam Resistance in <em>Enterobacterales</em> and <span class="named-content genus-species" id="named-content-1">Pseudomonas aeruginosa</span>
    Bacteriology
    A Selective Culture Medium for Screening Ceftazidime-Avibactam Resistance in Enterobacterales and Pseudomonas aeruginosa

    The SuperCAZ/AVI medium was developed for screening ceftazidime-avibactam (CZA) resistance among Gram-negative bacteria (Enterobacterales and Pseudomonas aeruginosa). It was evaluated using 50 CZA-susceptible and 42 CZA-resistant Gram-negative isolates. Its sensitivity and specificity of detection were 100%. Excellent performance of the medium was also...

    Mustafa Sadek, Laurent Poirel, Camille Tinguely, Patrice Nordmann
  • “Switching Partners”: Piperacillin-Avibactam Is a Highly Potent Combination against Multidrug-Resistant <em>Burkholderia cepacia</em> Complex and <em>Burkholderia gladioli</em> Cystic Fibrosis Isolates
    Bacteriology
    “Switching Partners”: Piperacillin-Avibactam Is a Highly Potent Combination against Multidrug-Resistant Burkholderia cepacia Complex and Burkholderia gladioli Cystic Fibrosis Isolates

    In persons with cystic fibrosis (CF), airway infection with Burkholderia cepacia complex (Bcc) species or Burkholderia gladioli presents a significant challenge due to inherent resistance to multiple antibiotics. Two chromosomally encoded inducible β-lactamases, a Pen-like class A and AmpC are...

    Elise T. Zeiser, Scott A. Becka, Brigid M. Wilson, Melissa D. Barnes, John J. LiPuma, Krisztina M. Papp-Wallace
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