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Candida

  • New Names for Fungi of Medical Importance: Can We Have Our Cake and Eat It Too?
    Letter to the Editor
    New Names for Fungi of Medical Importance: Can We Have Our Cake and Eat It Too?
    Sarah E. Kidd, Catriona L. Halliday, Brendan McMullan, Sharon C.-A. Chen, Juliet Elvy
  • Name Changes for Fungi of Medical Importance, 2018 to 2019
    Minireview
    Name Changes for Fungi of Medical Importance, 2018 to 2019

    The current article summarizes recent changes in nomenclature for fungi of medical importance published in the years 2018 to 2019, including new species and revised names for existing ones. Many of the revised names have been widely adopted without further discussion. However, those that concern common pathogens of humans may take longer to achieve general usage, with new and current names reported together to engender increasing...

    Andrew M. Borman, Elizabeth M. Johnson
  • Human Infections Caused by Clonally Related African Clade (Clade III) Strains of <span class="named-content genus-species" id="named-content-1">Candida auris</span> in the Greater Houston Region
    Mycology
    Human Infections Caused by Clonally Related African Clade (Clade III) Strains of Candida auris in the Greater Houston Region

    Candida auris is a pathogen of considerable public health importance. It was first reported in 2009. Five clades, determined by genomic analysis and named by the distinct regions where they were initially identified, have been defined. We previously completed a draft genome sequence of an African clade (clade III) strain cultured from the urine of a patient...

    S. Wesley Long, Matthew Ojeda Saavedra, Paul A. Christensen, James M. Musser, Randall J. Olsen
  • Open Access
    Multicenter Evaluation of a PCR-Based Digital Microfluidics and Electrochemical Detection System for the Rapid Identification of 15 Fungal Pathogens Directly from Positive Blood Cultures
    Mycology
    Multicenter Evaluation of a PCR-Based Digital Microfluidics and Electrochemical Detection System for the Rapid Identification of 15 Fungal Pathogens Directly from Positive Blood Cultures

    Routine identification of fungal pathogens from positive blood cultures by culture-based methods can be time-consuming, delaying treatment with appropriate antifungal agents. The GenMark Dx ePlex investigational use only blood culture identification fungal pathogen panel (BCID-FP) rapidly detects 15 fungal targets simultaneously in blood culture samples positive for fungi by Gram staining. We aimed to determine the performance of the...

    Sean X. Zhang, Karen C. Carroll, Shawna Lewis, Marissa Totten, Peter Mead, Linoj Samuel, Lisa L. Steed, Frederick S. Nolte, Adam Thornberg, Jennifer L. Reid, Natalie N. Whitfield, N. Esther Babady
  • Capability of Fluorescent Capillary Electrophoresis To Distinguish Species of the <em>Candida parapsilosis</em> Complex
    Letter to the Editor
    Capability of Fluorescent Capillary Electrophoresis To Distinguish Species of the Candida parapsilosis Complex
    Iva Kotásková, Hana Obručova, Veronika Lýčková, Filip Růžička, Tomáš Freiberger
  • Fluorescent Capillary Electrophoresis Is Superior to Culture in Detecting <em>Candida</em> Species from Samples of Urinary Catheters and Ureteral Stents with Mono- or Polyfungal Biofilm Growth
    Mycology
    Fluorescent Capillary Electrophoresis Is Superior to Culture in Detecting Candida Species from Samples of Urinary Catheters and Ureteral Stents with Mono- or Polyfungal Biofilm Growth

    Molecular techniques in fungal detection and identification represent an efficient complementary diagnostic tool which is increasingly used to overcome limitations of routinely used culture techniques. The aim of this study was to characterize Candida sp.

    Hana Obručová, Iva Kotásková, Radka Tihelková, Veronika Holá, Filip Růžička, Tomáš Freiberger
  • Are <em>In Vitro</em> Susceptibilities to Azole Antifungals Predictive of Clinical Outcome in the Treatment of Candidemia?
    Minireview
    Are In Vitro Susceptibilities to Azole Antifungals Predictive of Clinical Outcome in the Treatment of Candidemia?

    The purpose of this review is to critically analyze published data evaluating the impact of azole pharmacokinetic and pharmacodynamic parameters, MICs, and Candida species on clinical outcomes in patients with candidemia. Clinical breakpoints (CBPs) for fluconazole and voriconazole, which are used to determine susceptibility, have been defined by the Clinical and...

    Twisha S. Patel, Peggy L. Carver, Gregory A. Eschenauer
  • Mycology
    Comparative Analysis of the Wako β-Glucan Test and the Fungitell Assay for Diagnosis of Candidemia and Pneumocystis jirovecii Pneumonia
    Ricarda Friedrich, Elfriede Rappold, Christian Bogdan, Jürgen Held
  • Letter to the Editor
    Viability of Candida auris and Other Candida Species after Various Matrix-Assisted Laser Desorption Ionization–Time of Flight (MALDI-TOF) Mass Spectrometry-Based Extraction Protocols
    Alana Sterkel, Allen Bateman, Ann Valley, David Warshauer
  • Mycology
    In Vitro Evaluation of BacT/Alert FA Blood Culture Bottles and T2Candida Assay for Detection of Candida in the Presence of Antifungals

    The T2Candida assay is a novel, non-culture-based assay for the diagnosis of candidemia directly from whole blood. The impact of antifungals on the performance of the T2Candida assay and blood culture bottles has not been well described.

    Nicholas D. Beyda, Jonathan Amadio, Jose R. Rodriguez, Karen Malinowski, Kevin W. Garey, Audrey Wanger, Luis Ostrosky-Zeichner

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