community-acquired sepsis

  • Open Access
    Viruses in Vietnamese Patients Presenting with Community-Acquired Sepsis of Unknown Cause
    Virology
    Viruses in Vietnamese Patients Presenting with Community-Acquired Sepsis of Unknown Cause

    Community-acquired (CA) sepsis is a major public health problem worldwide, yet the etiology remains unknown for >50% of the patients. Here we applied metagenomic next-generation sequencing (mNGS) to characterize the human virome in 492 clinical samples (384 sera, 92 pooled nasal and throat swabs, 10 stools, and 6 cerebrospinal fluid samples) from 386 patients (213 adults and 173 children) presenting with CA sepsis who were recruited...

    Nguyen To Anh, Nguyen Thi Thu Hong, Le Nguyen Truc Nhu, Tran Tan Thanh, Chuen-Yen Lau, Direk Limmathurotsakul, Xutao Deng, Motiur Rahman, Nguyen Van Vinh Chau, H. Rogier van Doorn, Guy Thwaites, Eric Delwart, Le Van Tan
    and for the Southeast Asia Infectious Disease Clinical Research Network
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