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Journal of Clinical Microbiology
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Helicobacter pylori

  • <span class="named-content genus-species" id="named-content-1">Helicobacter pylori</span> Antimicrobial Resistance and Gene Variants in High- and Low-Gastric-Cancer-Risk Populations
    Bacteriology
    Helicobacter pylori Antimicrobial Resistance and Gene Variants in High- and Low-Gastric-Cancer-Risk Populations

    Colombia, South America has one of the world’s highest burdens of Helicobacter pylori infection and gastric cancer. While multidrug antibiotic regimens can effectively eradicate H. pylori, treatment efficacy is being jeopardized by the emergence of antibiotic-resistant...

    Anthony Mannion, JoAnn Dzink-Fox, Zeli Shen, M. Blanca Piazuelo, Keith T. Wilson, Pelayo Correa, Richard M. Peek, M. Constanza Camargo, James G. Fox
  • Diagnostic Accuracy of a Noninvasive Test for Detection of <span class="named-content genus-species" id="named-content-1">Helicobacter pylori</span> and Resistance to Clarithromycin in Stool by the Amplidiag <span class="named-content genus-species" id="named-content-2">H. pylori</span>+ClariR Real-Time PCR Assay
    Bacteriology
    Diagnostic Accuracy of a Noninvasive Test for Detection of Helicobacter pylori and Resistance to Clarithromycin in Stool by the Amplidiag H. pylori+ClariR Real-Time PCR Assay

    The noninvasive detection of Helicobacter pylori and its resistance to clarithromycin could revolutionize the management of H. pylori-infected patients by tailoring eradication treatment without any need for endoscopy when histology is not necessary. Several real-time PCR tests performed on stools...

    Maxime Pichon, Benoit Pichard, Thierry Barrioz, Chloé Plouzeau, Vincent Croquet, Ginette Fotsing, Alexandre Chéron, Éric Vuillemin, Marc Wangermez, Paul-Arthur Haineaux, Philippe Vasseur, Quentin Thiebault, Clémence Lefèvre, Anaïs de Singly, Julie Cremniter, Lauranne Broutin, Anthony Michaud, Christine Silvain, Christophe Burucoa
  • <span class="named-content genus-species" id="named-content-1">Helicobacter pylori</span> Infections in the Bronx, New York: Surveying Antibiotic Susceptibility and Strain Lineage by Whole-Genome Sequencing
    Bacteriology
    Helicobacter pylori Infections in the Bronx, New York: Surveying Antibiotic Susceptibility and Strain Lineage by Whole-Genome Sequencing

    The emergence of drug resistance in Helicobacter pylori has resulted in a greater need for susceptibility-guided treatment. While the alleles associated with resistance to clarithromycin and levofloxacin have been defined, there are limited data regarding the molecular mechanisms underlying resistance to other antimicrobials. Using...

    Rajagopalan Saranathan, Michael H. Levi, Alice R. Wattam, Adel Malek, Emmanuel Asare, Daniel S. Behin, Debra H. Pan, William R. Jacobs, Wendy A. Szymczak
  • <span class="named-content genus-species" id="named-content-1">Helicobacter pylori</span> Mutations Detected by Next-Generation Sequencing in Formalin-Fixed, Paraffin-Embedded Gastric Biopsy Specimens Are Associated with Treatment Failure
    Bacteriology
    Helicobacter pylori Mutations Detected by Next-Generation Sequencing in Formalin-Fixed, Paraffin-Embedded Gastric Biopsy Specimens Are Associated with Treatment Failure

    Helicobacter pylori antibiotic resistance is widespread and increasing worldwide. Routine detection of H. pylori mutations that invoke antimicrobial resistance may be a useful approach to guide antimicrobial therapy and possibly avert treatment failure.

    Behtash G. Nezami, Mehul Jani, David Alouani, Daniel D. Rhoads, Navid Sadri
  • Evaluation of a Novel Stool Antigen Rapid Test Kit for Detection of <span class="named-content genus-species" id="named-content-1">Helicobacter pylori</span> Infection
    Bacteriology
    Evaluation of a Novel Stool Antigen Rapid Test Kit for Detection of Helicobacter pylori Infection

    The Quick Chaser H. pylori (QCP), which is a novel antigen detection kit for Helicobacter pylori, was developed recently. The previous examination kits targeted the catalase of H. pylori; however, this new test kit, to the best of...

    Toshihiko Kakiuchi, Masumi Okuda, Kazutoshi Hashiguchi, Ichiro Imamura, Aiko Nakayama, Muneo Matsuo
  • Bacteriology
    Droplet Digital PCR-Based Detection of Clarithromycin Resistance in Helicobacter pylori Isolates Reveals Frequent Heteroresistance
    Lu Sun, Sarah Talarico, Lena Yao, Lihua He, Steve Self, Yuanhai You, Huifang Zhang, Yiyao Zhang, Yongjun Guo, Guodong Liu, Nina R. Salama, Jianzhong Zhang
  • Bacteriology
    A Novel Stool PCR Test for Helicobacter pylori May Predict Clarithromycin Resistance and Eradication of Infection at a High Rate
    Erin Beckman, Ilaria Saracino, Giulia Fiorini, Courtney Clark, Vladimir Slepnev, Denise Patel, Clarissa Gomez, Reddy Ponaka, Vecheslav Elagin, Dino Vaira
  • CASE REPORTS
    Helicobacter pylori Bacteremia with Sepsis Syndrome
    Xiang Y. Han, Jeffrey J. Tarrand, Burton F. Dickey, Francisco J. Esteva
  • Bacteriology
    High Prevalence of Clarithromycin Resistance and cagA, vacA, iceA2, and babA2 Genotypes of Helicobacter pylori in Brazilian Children
    Gabriella T. Garcia, Katia R. S. Aranda, Manoel E. P. Gonçalves, Silvia R. Cardoso, Kiyoshi Iriya, Neusa P. Silva, Isabel C. A. Scaletsky
  • Bacteriology
    Molecular Basis of Pathogenicity in Helicobacter pylori Clinical Isolates
    Ivy Bastos Ramis, Tesiê Leopoldo Fonseca, Ernani Pinho de Moraes, Márcia Silveira Fernandes, Raul Mendoza-Sassi, Obirajara Rodrigues, Carlos Renan Varela Juliano, Carlos James Scaini, Pedro Eduardo Almeida da Silva

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