infectious disease
- ImmunoassaysQuantitative Measurement of Anti-SARS-CoV-2 Antibodies: Analytical and Clinical Evaluation
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). While molecular-based testing is used to diagnose COVID-19, serologic testing of antibodies specific to SARS-CoV-2 is used to detect past infection.
- ParasitologyRapid Diagnostic Tests for Trypanosoma cruzi Infection: Field Evaluation of Two Registered Kits in a Region of Endemicity and a Region of Nonendemicity in Argentina
Infection by Trypanosoma cruzi (Chagas disease [ChD]) affects around 7 million people in the Americas, most of whom are unaware of their status due to lack of clinical manifestations and poor access to diagnosis. Rapid diagnostic tests (RDTs) are widely used for screening for different infections (HIV, hepatitis B, and syphilis), and their application for ChD would...
- Photo QuizAnswer to November 2020 Photo Quiz
- CommentarySetup, Validation, and Quality Control of a Centralized Whole-Genome-Sequencing Laboratory: Lessons Learned
Routine use of whole-genome analysis for infectious diseases can be used to enlighten various scenarios pertaining to public health, including identification of microbial pathogens, relating individual cases to an outbreak of infectious disease, establishing an association between an outbreak of food poisoning and a specific food vehicle, inferring drug susceptibility, source tracing of contaminants, and study of variations in the...
- Mycobacteriology and Aerobic ActinomycetesTarget-Specific Assay for Rapid and Quantitative Detection of Mycobacterium chimaera DNA