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liquid biopsy

  • Open Access
    Investigation of Preanalytical Variables Impacting Pathogen Cell-Free DNA in Blood and Urine
    Bacteriology
    Investigation of Preanalytical Variables Impacting Pathogen Cell-Free DNA in Blood and Urine

    Pathogen cell-free DNA (pcfDNA) in blood and urine is an attractive biomarker; however, the impact of preanalytical factors is not well understood. Blood and urine samples from healthy donors spiked with cfDNA from Mycobacterium tuberculosis, Salmonella enterica,...

    Kanagavel Murugesan, Catherine A. Hogan, Zaida Palmer, Byron Reeve, Grant Theron, Alfred Andama, Akos Somoskovi, Amy Steadman, Damian Madan, Jason Andrews, Julio Croda, Malaya K. Sahoo, Adithya Cattamanchi, Benjamin A. Pinsky, Niaz Banaei
  • Open Access
    Toward the Development of a Circulating Free DNA-Based <em>In Vitro</em> Diagnostic Test for Infectious Diseases: a Review of Evidence for Tuberculosis
    Minireview
    Toward the Development of a Circulating Free DNA-Based In Vitro Diagnostic Test for Infectious Diseases: a Review of Evidence for Tuberculosis

    The detection of circulating free DNA (cfDNA) has transformed the field of oncology and prenatal diagnostics. Clinical application of cfDNA for disease diagnosis and monitoring, however, is relatively recent in the field of infectious disease.

    B. Leticia Fernández-Carballo, Tobias Broger, Romain Wyss, Niaz Banaei, Claudia M. Denkinger
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