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malaria

  • Open Access
    Simultaneous Quantification of <em>Plasmodium</em> Antigens and Host Factor C-Reactive Protein in Asymptomatic Individuals with Confirmed Malaria by Use of a Novel Multiplex Immunoassay
    Immunoassays
    Simultaneous Quantification of Plasmodium Antigens and Host Factor C-Reactive Protein in Asymptomatic Individuals with Confirmed Malaria by Use of a Novel Multiplex Immunoassay

    Malaria rapid diagnostic tests (RDTs) primarily detect Plasmodium falciparum antigen histidine-rich protein 2 (HRP2) and the malaria-conserved antigen lactate dehydrogenase (LDH) for P. vivax and other malaria species. The performance of RDTs and their utility is dependent on circulating antigen...

    Ihn Kyung Jang, Abby Tyler, Chris Lyman, Maria Kahn, Michael Kalnoky, John C. Rek, Emmanuel Arinaitwe, Harriet Adrama, Maxwell Murphy, Mallika Imwong, Clare L. Ling, Stephane Proux, Warat Haohankhunnatham, Melissa Rist, Annette M. Seilie, Amelia Hanron, Glenda Daza, Ming Chang, Smita Das, Rebecca Barney, Andrew Rashid, Jordi Landier, David S. Boyle, Sean C. Murphy, James S. McCarthy, François Nosten, Bryan Greenhouse, Gonzalo J. Domingo
  • Open Access
    Parasitology
    Operational Performance of a Plasmodium falciparum Ultrasensitive Rapid Diagnostic Test for Detection of Asymptomatic Infections in Eastern Myanmar

    In the Greater Mekong Subregion in Southeast Asia, malaria elimination strategies need to target all Plasmodium falciparum parasites, including those carried asymptomatically. More than 70% of asymptomatic carriers are not detected by current rapid diagnostic tests (RDTs) or microscopy.

    Jordi Landier, Warat Haohankhunnatham, Smita Das, Kamonchanok Konghahong, Peter Christensen, Jathee Raksuansak, Pase Phattharakokoedbun, Ladda Kajeechiwa, May Myo Thwin, Ihn Kyung Jang, Mallika Imwong, Jacher Wiladphaingern, Khin Maung Lwin, Clare Ling, Stephane Proux, Gonzalo J. Domingo, Gilles Delmas, François H. Nosten
  • Parasitology
    Malaria Diagnostic Practices in U.S. Laboratories in 2017

    In the United States, the gold standard for malaria diagnosis is microscopic blood smear examination. Because malaria is not endemic in the United States, diagnostic capabilities may be limited, causing delays in diagnosis and increased morbidity and mortality.

    Christopher Prestel, Kathrine R. Tan, Francisca Abanyie, Robert Jerris, Julie R. Gutman
  • Parasitology
    Detection of Plasmodium Species by High-Resolution Melt Analysis of DNA from Blood Smears Acquired in Southwestern Uganda
    Kennedy Kassaza, Darwin J. Operario, Dan Nyehangane, K. C. Coffey, Mary Namugosa, Lena Turkheimer, Patrick Ojuka, Patrick Orikiriza, Juliet Mwanga-Amumpaire, Frederick Byarugaba, Joel Bazira, Jennifer L. Guler, Christopher C. Moore, Yap Boum
  • Letter to the Editor
    Modern Hematology Analyzers Are Very Useful for Diagnosis of Malaria and, Crucially, May Help Avoid Misdiagnosis
    Thomas Hanscheid, Martin P. Grobusch
  • Letter to the Editor
    Reply to “Modern Hematology Analyzers Are Very Useful for Diagnosis of Malaria and, Crucially, May Help Avoid Misdiagnosis”
    Blaine A. Mathison, Bobbi S. Pritt
  • Parasitology
    Detection of Plasmodium Infection by the illumigene Malaria Assay Compared to Reference Microscopy and Real-Time PCR
    Candace Rypien, Barbara Chow, Wilson W. Chan, Deirdre L. Church, Dylan R. Pillai
  • Minireview
    Update on Malaria Diagnostics and Test Utilization
    Blaine A. Mathison, Bobbi S. Pritt
  • Parasitology
    Improving the Specificity of Plasmodium falciparum Malaria Diagnosis in High-Transmission Settings with a Two-Step Rapid Diagnostic Test and Microscopy Algorithm
    Moses Murungi, Travis Fulton, Raquel Reyes, Michael Matte, Moses Ntaro, Edgar Mulogo, Dan Nyehangane, Jonathan J. Juliano, Mark J. Siedner, Yap Boum, Ross M. Boyce
  • Parasitology
    Evaluation of the Parasight Platform for Malaria Diagnosis
    Yochay Eshel, Arnon Houri-Yafin, Hagai Benkuzari, Natalie Lezmy, Mamta Soni, Malini Charles, Jayanthi Swaminathan, Hilda Solomon, Pavithra Sampathkumar, Zul Premji, Caroline Mbithi, Zaitun Nneka, Simon Onsongo, Daniel Maina, Sarah Levy-Schreier, Caitlin Lee Cohen, Dan Gluck, Joseph Joel Pollak, Seth J. Salpeter

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