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polymerase chain reaction

  • Molecular Microbiological and Immune Characterization of a Cohort of Patients Diagnosed with Early Lyme Disease
    Bacteriology
    Molecular Microbiological and Immune Characterization of a Cohort of Patients Diagnosed with Early Lyme Disease

    Lyme disease is a tick-borne infection caused by the bacteria Borrelia burgdorferi. Current diagnosis of early Lyme disease relies heavily on clinical criteria, including the presence of an erythema migrans rash. The sensitivity of current gold-standard diagnostic tests relies upon antibody formation, which is typically delayed and thus of limited utility in early...

    Michael R. Mosel, Alison W. Rebman, Heather E. Carolan, Tristan Montenegro, Robert Lovari, Steven E. Schutzer, David J. Ecker, Ting Yang, Nitya S. Ramadoss, William H. Robinson, Mark J. Soloski, Mark W. Eshoo, John N. Aucott
  • Evaluation of IgM Lateral Flow Assay as a Screening Tool for <em>Mycoplasma pneumoniae</em> Infection in Childhood Pneumonia
    Letter to the Editor
    Evaluation of IgM Lateral Flow Assay as a Screening Tool for Mycoplasma pneumoniae Infection in Childhood Pneumonia
    Patrick M. Meyer Sauteur, Elena Pánisová, Lucas M. Bachmann, Lilliam Ambroggio, Christoph Berger
  • Comparison of Loop-Mediated Isothermal Amplification and Real-Time PCR Assays for Detection of <span class="named-content genus-species" id="named-content-1">Strongyloides</span> Larvae in Different Specimen Matrices
    Parasitology
    Comparison of Loop-Mediated Isothermal Amplification and Real-Time PCR Assays for Detection of Strongyloides Larvae in Different Specimen Matrices

    Strongyloides stercoralis can cause disease that ranges from asymptomatic chronic infection to fatal hyperinfection. Diagnosis from stool can be challenging because the most sensitive conventional tests require live larvae to be effective and there can be low larval output in chronic infection.

    Matthew R. Watts, Rady Kim, Vishal Ahuja, Gemma J. Robertson, Yasmin Sultana, Michael C. Wehrhahn, Richard S. Bradbury, Gwendolyn L. Gilbert, Rogan Lee
  • Clinical Veterinary Microbiology
    Development of Serotype-Specific PCR Assays for Typing of Haemophilus parasuis Isolates Circulating in Southern China
    Aiqing Jia, Ruyue Zhou, Huiying Fan, Kaijie Yang, Jianmin Zhang, Yindi Xu, Guiping Wang, Ming Liao
  • Bacteriology
    Accurate Detection of Methicillin-Resistant Staphylococcus aureus in Mixtures by Use of Single-Bacterium Duplex Droplet Digital PCR
    Jun Luo, Junhua Li, Hang Yang, Junping Yu, Hongping Wei
  • Open Access
    Mycology
    Performance of a Quantitative PCR-Based Assay and Beta-d-Glucan Detection for Diagnosis of Invasive Candidiasis in Very-Low-Birth-Weight Preterm Neonatal Patients (CANDINEO Study)
    Jose Tomas Ramos, Sonia Villar, Emilio Bouza, Elena Bergon-Sendin, Alfredo Perez Rivilla, Caridad Tapia Collados, Mariano Andreu, Candelaria Santana Reyes, María Isolina Campos-Herrero, Jon López de Heredia, María Cruz López Herrera, Paloma Anguita Alonso, Carmen Rosa Pallás-Alonso, Manuel Cuenca-Estrella, the CANDINEO Study Group
  • Bacteriology
    A Novel Stool PCR Test for Helicobacter pylori May Predict Clarithromycin Resistance and Eradication of Infection at a High Rate
    Erin Beckman, Ilaria Saracino, Giulia Fiorini, Courtney Clark, Vladimir Slepnev, Denise Patel, Clarissa Gomez, Reddy Ponaka, Vecheslav Elagin, Dino Vaira
  • Open Access
    Mycology
    Rapid and Accurate Molecular Identification of the Emerging Multidrug-Resistant Pathogen Candida auris
    Milena Kordalewska, Yanan Zhao, Shawn R. Lockhart, Anuradha Chowdhary, Indira Berrio, David S. Perlin
  • Minireview
    Applications of Digital PCR for Clinical Microbiology
    Jane Kuypers, Keith R. Jerome
  • Mycology
    Usefulness of Two Aspergillus PCR Assays and Aspergillus Galactomannan and β-d-Glucan Testing of Bronchoalveolar Lavage Fluid for Diagnosis of Chronic Pulmonary Aspergillosis
    Naohisa Urabe, Susumu Sakamoto, Go Sano, Junko Suzuki, Akira Hebisawa, Yasuhiko Nakamura, Kazuya Koyama, Yoshikazu Ishii, Kazuhiro Tateda, Sakae Homma

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