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serum

  • An Evaluation of the Performance of the IMMY <em>Aspergillus</em> Galactomannan Enzyme-Linked Immunosorbent Assay When Testing Serum To Aid in the Diagnosis of Invasive Aspergillosis
    Mycology
    An Evaluation of the Performance of the IMMY Aspergillus Galactomannan Enzyme-Linked Immunosorbent Assay When Testing Serum To Aid in the Diagnosis of Invasive Aspergillosis

    The objectives of this study were to evaluate the performance of the recently released IMMY Aspergillus galactomannan enzyme immunoassay (IMMY GM-EIA) when testing serum samples and to identify the optimal galactomannan index (GMI) positivity threshold for the diagnosis of invasive aspergillosis (IA). This was a retrospective case/control study, comprising 175 serum samples obtained from 131 patients, 35 of whom had probable or...

    P. Lewis White, Jessica S. Price, Raquel Posso, Lorna Vale, Matthijs Backx
  • Evaluation of the Performance of the IMMY sona <em>Aspergillus</em> Galactomannan Lateral Flow Assay When Testing Serum To Aid in Diagnosis of Invasive Aspergillosis
    Mycology
    Evaluation of the Performance of the IMMY sona Aspergillus Galactomannan Lateral Flow Assay When Testing Serum To Aid in Diagnosis of Invasive Aspergillosis

    Management of invasive aspergillosis has been improved by biomarker assays, but limited accessibility and batch testing limit the impact. Lateral flow assays (LFA) are a simple method for use outside specialist centers, provided performance is acceptable. The objective of this study was to determine the performance of the recently released IMMY sona Aspergillus LFA when testing serum samples. The study took the form of a...

    P. Lewis White, Jessica S. Price, Raquel Posso, Morgan Cutlan-Vaughan, Lorna Vale, Matthijs Backx
  • Comparison of Loop-Mediated Isothermal Amplification and Real-Time PCR Assays for Detection of <span class="named-content genus-species" id="named-content-1">Strongyloides</span> Larvae in Different Specimen Matrices
    Parasitology
    Comparison of Loop-Mediated Isothermal Amplification and Real-Time PCR Assays for Detection of Strongyloides Larvae in Different Specimen Matrices

    Strongyloides stercoralis can cause disease that ranges from asymptomatic chronic infection to fatal hyperinfection. Diagnosis from stool can be challenging because the most sensitive conventional tests require live larvae to be effective and there can be low larval output in chronic infection.

    Matthew R. Watts, Rady Kim, Vishal Ahuja, Gemma J. Robertson, Yasmin Sultana, Michael C. Wehrhahn, Richard S. Bradbury, Gwendolyn L. Gilbert, Rogan Lee
  • Open Access
    Bacteriology
    Evaluation of a Rapid Diagnostic Test for Detection of Burkholderia pseudomallei in the Lao People's Democratic Republic
    Kate L. Woods, Latsaniphone Boutthasavong, Caoimhe NicFhogartaigh, Sue J. Lee, Viengmon Davong, David P. AuCoin, David A. B. Dance
  • Mycology
    Diagnostic Value of Galactomannan Antigen Test in Serum and Bronchoalveolar Lavage Fluid Samples from Patients with Nonneutropenic Invasive Pulmonary Aspergillosis
    Wei Zhou, Hongxing Li, Yan Zhang, Mei Huang, Qian He, Pei Li, Fang Zhang, Yi Shi, Xin Su
  • Bacteriology
    Interlaboratory Evaluation of Different Extraction and Real-Time PCR Methods for Detection of Coxiella burnetii DNA in Serum
    Jeroen J. H. C. Tilburg, Willem J. G. Melchers, Annika M. Pettersson, John W. A. Rossen, Mirjam H. A. Hermans, Erik J. van Hannen, Marrigje H. Nabuurs-Franssen, Maaike C. de Vries, Alphons M. Horrevorts, Corné H. W. Klaassen
  • Parasitology
    Rapid Detection of Trypanosoma cruzi in Human Serum by Use of an Immunochromatographic Dipstick Test
    Richard Reithinger, Mario J. Grijalva, Rosa F. Chiriboga, Belkisyolé Alarcón de Noya, Jaime R. Torres, Norma Pavia-Ruz, Pablo Manrique-Saide, Marta V. Cardinal, Ricardo E. Gürtler
  • Bacteriology
    Clinical Potential of C-Reactive Protein and Procalcitonin Serum Concentrations To Guide Differential Diagnosis and Clinical Management of Pneumococcal and Legionella Pneumonia
    Rosa Bellmann-Weiler, Mathias Ausserwinkler, Katharina Kurz, Igor Theurl, Guenter Weiss
  • Virology
    Hepatitis E Virus (HEV) Strains in Serum Samples Can Replicate Efficiently in Cultured Cells Despite the Coexistence of HEV Antibodies: Characterization of HEV Virions in Blood Circulation
    Masaharu Takahashi, Toshinori Tanaka, Hideyuki Takahashi, Yu Hoshino, Shigeo Nagashima, Jirintai, Hitoshi Mizuo, Yasuyuki Yazaki, Tomofumi Takagi, Masahiro Azuma, Eiji Kusano, Norio Isoda, Kentaro Sugano, Hiroaki Okamoto
  • Parasitology
    Identification of Novel Diagnostic Serum Biomarkers for Chagas' Disease in Asymptomatic Subjects by Mass Spectrometric Profiling
    Momar Ndao, Terry W. Spithill, Rebecca Caffrey, Hongshan Li, Vladimir N. Podust, Regis Perichon, Cynthia Santamaria, Alberto Ache, Mark Duncan, Malcolm R. Powell, Brian J. Ward

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