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Journal of Clinical Microbiology
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Streptococcus pyogenes

  • Open Access
    Population Genomic Molecular Epidemiological Study of Macrolide-Resistant <span class="named-content genus-species" id="named-content-1">Streptococcus pyogenes</span> in Iceland, 1995 to 2016: Identification of a Large Clonal Population with a <em>pbp2x</em> Mutation Conferring Reduced <em>In Vitro</em> β-Lactam Susceptibility
    Epidemiology
    Population Genomic Molecular Epidemiological Study of Macrolide-Resistant Streptococcus pyogenes in Iceland, 1995 to 2016: Identification of a Large Clonal Population with a pbp2x Mutation Conferring Reduced In Vitro β-Lactam Susceptibility

    Resistance to macrolide antibiotics is a global concern in the treatment of Streptococcus pyogenes (group A Streptococcus [GAS]) infections. In Iceland, since the detection of the first macrolide-resistant isolate in 1998, three epidemic waves of macrolide-resistant GAS infections have occurred, with peaks in 1999, 2004, and 2008. We conducted whole-genome...

    Sara B. Southon, Stephen B. Beres, Priyanka Kachroo, Matthew Ojeda Saavedra, Helga Erlendsdóttir, Gunnsteinn Haraldsson, Prasanti Yerramilli, Layne Pruitt, Luchang Zhu, James M. Musser, Karl G. Kristinsson
  • Group A Streptococcus Testing in Pediatrics: the Move to Point-of-Care Molecular Testing
    Minireview
    Group A Streptococcus Testing in Pediatrics: the Move to Point-of-Care Molecular Testing

    Each year, there are an estimated 11 million visits to ambulatory care centers for pharyngitis in children between the ages of 3 and 18 years. While there are many causes of pediatric pharyngitis, group A streptococcal pharyngitis represents 15 to 30% of infections and is the only cause for which treatment is recommended. Unfortunately, clinical suspicion is insufficient for the accurate diagnosis of group A streptococcal pharyngitis,...

    Thomas Z. Thompson, Allison R. McMullen
  • Multicenter Clinical Evaluation of the Automated Aries Group A Strep PCR Assay from Throat Swabs
    Bacteriology
    Multicenter Clinical Evaluation of the Automated Aries Group A Strep PCR Assay from Throat Swabs

    Group A Streptococcus (GAS) is one of the leading causes of bacterial pharyngitis. Early GAS diagnosis is critical for appropriate antibiotic administration that reduces the risk of GAS sequelae and limits spread of the infection.

    N. Kanwar, J. Crawford, C. Ulen, T. S. Uphoff, J. Dien Bard, R. Dunn, A. Drain, R. Selvarangan
  • Open Access
    Bacteriology
    Epidemiological and Molecular Characterization of an Invasive Group A Streptococcus emm32.2 Outbreak
    Jennifer E. Cornick, Anmol M. Kiran, Roberto Vivancos, Jon Van Aartsen, Jenny Clarke, Edward Bevan, Mansoor Alsahag, Maaike Alaearts, Laura Bricio Moreno, Howard F. Jenkinson, Angela H. Nobbs, James Anson, Aras Kadioglu, Neil French, Dean B. Everett
  • CASE REPORTS
    Axillary Abscess Complicated by Venous Thrombosis: Identification of Streptococcus pyogenes by 16S PCR
    Fredrik Kahn, Adam Linder, Ann Cathrine Petersson, Bertil Christensson, Magnus Rasmussen
  • ERRATA
    Clinical and Microbial Characteristics of Invasive Streptococcus pyogenes Disease in New Caledonia, a Region in Oceania with a High Incidence of Acute Rheumatic Fever
    S. Le Hello, A. Doloy, F. Baumann, N. Roques, P. Coudene, B. Rouchon, F. Lacassin, A. Bouvet
  • Epidemiology
    Streptococcus pyogenes Isolates Causing Severe Infections in Norway in 2006 to 2007: emm Types, Multilocus Sequence Types, and Superantigen Profiles
    Roger Meisal, Ida K. G. Andreasson, E. Arne Høiby, Ingeborg S. Aaberge, Terje E. Michaelsen, Dominique A. Caugant
  • Bacteriology
    Nonhemolytic Streptococcus pyogenes Isolates That Lack Large Regions of the sag Operon Mediating Streptolysin S Production
    Miho Yoshino, Somay Y. Murayama, Katsuhiko Sunaoshi, Takeaki Wajima, Miki Takahashi, Junko Masaki, Iku Kurokawa, Kimiko Ubukata
  • Epidemiology
    Clinical and Microbial Characteristics of Invasive Streptococcus pyogenes Disease in New Caledonia, a Region in Oceania with a High Incidence of Acute Rheumatic Fever
    S. Le Hello, A. Doloy, F. Baumann, N. Roques, P. Coudene, B. Rouchon, F. Lacassin, A. Bouvet
  • Epidemiology
    Subtyping of emm1 Group A Streptococci Causing Invasive Infections in France
    P. Bidet, E. Lesteven, C. Doit, S. Liguori, P. Mariani-Kurkdjian, S. Bonacorsi, E. Bingen

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