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Journal of Clinical Microbiology
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surveillance

  • Macrolide-Resistant <span class="named-content genus-species" id="named-content-1">Mycoplasma pneumoniae</span> in the United States as Determined from a National Surveillance Program
    Epidemiology
    Macrolide-Resistant Mycoplasma pneumoniae in the United States as Determined from a National Surveillance Program

    There are sparse data to indicate the extent that macrolide-resistant Mycoplasma pneumoniae (MRMp) occurs in the United States or its clinical significance. Between 2015 and 2018, hospitals in 8 states collected and stored respiratory specimens that tested positive for M. pneumoniae and sent them to...

    K. B. Waites, A. Ratliff, D. M. Crabb, L. Xiao, X. Qin, R. Selvarangan, Y.-W. Tang, X. Zheng, J. Dien Bard, T. Hong, M. Prichard, E. Brooks, S. Dallas, L. Duffy, E. Mixon, K. B. Fowler, T. P. Atkinson
  • A Rapid and Automated Sample-to-Result <span class="named-content genus-species" id="named-content-1">Candida auris</span> Real-Time PCR Assay for High-Throughput Testing of Surveillance Samples with the BD Max Open System
    Mycology
    A Rapid and Automated Sample-to-Result Candida auris Real-Time PCR Assay for High-Throughput Testing of Surveillance Samples with the BD Max Open System

    The multidrug-resistant yeast pathogen Candida auris continues to cause outbreaks and clusters of clinical cases worldwide. Previously, we developed a real-time PCR assay for the detection of C. auris from surveillance samples (L. Leach, Y. Zhu, and S. Chaturvedi, J Clin Microbiol 56:e01223-17, 2018...

    L. Leach, A. Russell, Y. Zhu, S. Chaturvedi, V. Chaturvedi
  • Carbapenem-Nonsusceptible <em>Pseudomonas aeruginosa</em> Isolates from Intensive Care Units in the United States: a Potential Role for New β-Lactam Combination Agents
    Epidemiology
    Carbapenem-Nonsusceptible Pseudomonas aeruginosa Isolates from Intensive Care Units in the United States: a Potential Role for New β-Lactam Combination Agents

    Pseudomonas aeruginosa, a frequent pathogen in the intensive care unit (ICU), has the propensity to develop antibiotic resistance. In particular, carbapenem-nonsusceptible (NS) P. aeruginosa poses tremendous challenges, and new antibiotics will be needed to treat this phenotype. Here we determine...

    Tomefa E. Asempa, David P. Nicolau, Joseph L. Kuti
  • Open Access
    Pathotyping the Zoonotic Pathogen <span class="named-content genus-species" id="named-content-1">Streptococcus suis</span>: Novel Genetic Markers To Differentiate Invasive Disease-Associated Isolates from Non-Disease-Associated Isolates from England and Wales
    Clinical Veterinary Microbiology
    Pathotyping the Zoonotic Pathogen Streptococcus suis: Novel Genetic Markers To Differentiate Invasive Disease-Associated Isolates from Non-Disease-Associated Isolates from England and Wales

    Streptococcus suis is one of the most important zoonotic bacterial pathogens of pigs, causing significant economic losses to the global swine industry. S. suis is also a very successful colonizer of mucosal surfaces, and commensal strains can be found in almost all pig populations worldwide, making...

    Thomas M. Wileman, Lucy A. Weinert, Kate J. Howell, Jinhong Wang, Sarah E. Peters, Susanna M. Williamson, Jerry M. Wells, Paul R. Langford, Andrew N. Rycroft, Brendan W. Wren, Duncan J. Maskell, Alexander W. Tucker
    and on behalf of the BRaDP1T Consortium
  • Open Access
    hicap: <em>In Silico</em> Serotyping of the <span class="named-content genus-species" id="named-content-1">Haemophilus influenzae</span> Capsule Locus
    Bacteriology
    hicap: In Silico Serotyping of the Haemophilus influenzae Capsule Locus

    Haemophilus influenzae exclusively colonizes the human nasopharynx and can cause a variety of respiratory infections as well as invasive diseases, including meningitis and sepsis. A key virulence determinant of H. influenzae is the polysaccharide capsule, of which six serotypes are known, each...

    Stephen C. Watts, Kathryn E. Holt
  • Rapid Emergence, Subsidence, and Molecular Detection of <em>Escherichia coli</em> Sequence Type 1193-<em>fimH64</em>, a New Disseminated Multidrug-Resistant Commensal and Extraintestinal Pathogen
    Epidemiology
    Rapid Emergence, Subsidence, and Molecular Detection of Escherichia coli Sequence Type 1193-fimH64, a New Disseminated Multidrug-Resistant Commensal and Extraintestinal Pathogen

    Escherichia coli sequence type 1193 (ST1193) is an emerging multidrug-resistant pathogen. We performed longitudinal and cross-sectional surveillance for ST1193 among clinical and fecal E. coli isolates from Minneapolis Veterans Affairs Medical Center (VAMC) patients and their household members,...

    James R. Johnson, Brian D. Johnston, Stephen B. Porter, Connie Clabots, Tricia L. Bender, Paul Thuras, Darren J. Trott, Rowland Cobbold, Joanne Mollinger, Patricia Ferrieri, Sarah Drawz, Ritu Banerjee
  • Bacteriology
    Multicenter Evaluation of the Xpert Carba-R Assay for Detection of Carbapenemase Genes in Gram-Negative Isolates

    This multicenter study evaluated the performance of the Cepheid Xpert Carba-R assay, a qualitative PCR test designed for the rapid detection of blaKPC, blaNDM, blaVIM, blaIMP, and blaOXA-48 carbapenem resistance genes from bacterial isolates grown on blood agar or MacConkey agar. The results were compared to those obtained from...

    Maria M. Traczewski, Edoardo Carretto, Rafael Canton, Nicholas M. Moore, for the Carba-R Study Team
  • Free
    Mycology
    Update from a 12-Year Nationwide Fungemia Surveillance: Increasing Intrinsic and Acquired Resistance Causes Concern
    K. M. T. Astvad, H. K. Johansen, B. L. Røder, F. S. Rosenvinge, J. D. Knudsen, L. Lemming, H. C. Schønheyder, R. K. Hare, L. Kristensen, L. Nielsen, J. B. Gertsen, E. Dzajic, M. Pedersen, C. Østergård, B. Olesen, T. S. Søndergaard, M. C. Arendrup
  • Free
    Virology
    Development of Envelope Protein Antigens To Serologically Differentiate Zika Virus Infection from Dengue Virus Infection
    Lakshmanane Premkumar, Matthew Collins, Stephen Graham, Guei-Jiun Alice Liou, Cesar A. Lopez, Ramesh Jadi, Angel Balmaseda, James A. Brackbill, Reynaldo Dietze, Erwin Camacho, Aruna D. De Silva, Camila Giuberti, Helena Lucia dos Reis, Tulika Singh, Holly Heimsath, Daniela Weiskopf, Alessandro Sette, Jorge E. Osorio, Sallie R. Permar, Michel J. Miley, Helen M. Lazear, Eva Harris, Aravinda M. de Silva
  • Free
    Virology
    Comparison of Four Serological Methods and Two Reverse Transcription-PCR Assays for Diagnosis and Surveillance of Zika Virus Infection
    Angel Balmaseda, José Victor Zambrana, Damaris Collado, Nadezna García, Saira Saborío, Douglas Elizondo, Juan Carlos Mercado, Karla Gonzalez, Cristhiam Cerpas, Andrea Nuñez, Davide Corti, Jesse J. Waggoner, Guillermina Kuan, Raquel Burger-Calderon, Eva Harris

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