virology
ImmunoassaysQuantitative Measurement of Anti-SARS-CoV-2 Antibodies: Analytical and Clinical EvaluationThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). While molecular-based testing is used to diagnose COVID-19, serologic testing of antibodies specific to SARS-CoV-2 is used to detect past infection.
MinireviewTaxonomic Changes for Human and Animal Viruses, 2018 to 2020The classification of viruses is relevant to a number of scientific and clinical disciplines, including the practice of diagnostic virology. Here, we provide an update to our previous review of taxonomic changes for disease-causing viruses in humans and vertebrate animals, covering changes between 2018 and 2020. Recent advances in virus taxonomy structure by the International Committee on Taxonomy of Viruses inform this update.
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Special Issue Letter to the EditorTest Agreement between Roche Cobas 6800 and Cepheid GeneXpert Xpress SARS-CoV-2 Assays at High Cycle Threshold Ranges
VirologyMetagenomic Next-Generation Sequencing for Identification and Quantitation of Transplant-Related DNA VirusesInfections with DNA viruses are frequent causes of morbidity and mortality in transplant recipients.
MinireviewTaxonomic Changes for Human and Animal Viruses, 2016 to 2018The classification of viruses provides the structure necessary to appreciate their biological diversity. Herein, we provide an update to our previous review of changes in viral taxonomy, covering changes between 2016 and 2018.
EpidemiologyPCR Detection of Respiratory Pathogens in Asymptomatic and Symptomatic AdultsThe frequency of viral respiratory pathogens in asymptomatic subjects is poorly defined. The aim of this study was to explore the prevalence of respiratory pathogens in the upper airways of asymptomatic adults, compared with a reference population of symptomatic patients sampled in the same centers during the same period.
VirologyDetection of Viruses in Clinical Samples by Use of Metagenomic Sequencing and Targeted Sequence CaptureMetagenomic shotgun sequencing (MSS) is a revolutionary approach to viral diagnostic testing that allows simultaneous detection of a broad range of viruses, detailed taxonomic assignment, and detection of mutations associated with antiviral drug resistance. To enhance sensitivity for virus detection, we previously developed ViroCap, a targeted sequence capture panel designed to enrich nucleic acid from a comprehensive set of eukaryotic...
