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Journal of Clinical Microbiology
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Xpert MTB/RIF Ultra

  • Free
    Automatic Identification of Individual <em>rpoB</em> Gene Mutations Responsible for Rifampin Resistance in <span class="named-content genus-species" id="named-content-1">Mycobacterium tuberculosis</span> by Use of Melting Temperature Signatures Generated by the Xpert MTB/RIF Ultra Assay
    Mycobacteriology and Aerobic Actinomycetes
    Automatic Identification of Individual rpoB Gene Mutations Responsible for Rifampin Resistance in Mycobacterium tuberculosis by Use of Melting Temperature Signatures Generated by the Xpert MTB/RIF Ultra Assay

    Molecular surveillance of rifampin-resistant Mycobacterium tuberculosis can help to monitor the transmission of the disease. The Xpert MTB/RIF Ultra assay detects mutations in the rifampin resistance-determining region (RRDR) of the rpoB gene by the use of melting temperature (Tm) information from 4 rpoB probes which can fall in...

    Yuan Cao, Heta Parmar, Ann Marie Simmons, Devika Kale, Kristy Tong, Deanna Lieu, David Persing, Robert Kwiatkowski, David Alland, Soumitesh Chakravorty
  • Open Access
    Added Value of Xpert MTB/RIF Ultra for Diagnosis of Pulmonary Tuberculosis in a Low-Prevalence Setting
    Mycobacteriology and Aerobic Actinomycetes
    Added Value of Xpert MTB/RIF Ultra for Diagnosis of Pulmonary Tuberculosis in a Low-Prevalence Setting

    Xpert MTB/RIF (Xpert) for direct molecular detection of Mycobacterium tuberculosis and rifampin resistance from clinical specimens has dramatically improved the diagnosis of tuberculosis (TB). Xpert MTB/RIF Ultra (Ultra) is proposed as a substitute of Xpert with increased sensitivity and improved rifampin resistance detection.

    Onya Opota, Fathiah Zakham, Jesica Mazza-Stalder, Laurent Nicod, Gilbert Greub, Katia Jaton
  • Mycobacteriology and Aerobic Actinomycetes
    Evaluation of the Xpert MTB/RIF Ultra Assay for Direct Detection of Mycobacterium tuberculosis Complex in Smear-Negative Extrapulmonary Samples
    Daniel Perez-Risco, David Rodriguez-Temporal, Ivan Valledor-Sanchez, Fernando Alcaide
  • Open Access
    Letter to the Editor
    Xpert Ultra Can Unambiguously Identify Specific Rifampin Resistance-Conferring Mutations
    Kamela C. S. Ng, Armand van Deun, Conor J. Meehan, Gabriela Torrea, Michèle Driesen, Siemon Gabriëls, Leen Rigouts, Emmanuel André, Bouke C. de Jong
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