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Journal of Clinical Microbiology
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Latest Articles

  • Diagnostic Accuracy of Four Commercial Triplex Immunochromatographic Tests for Rapid Detection of Rotavirus, Adenovirus, and Norovirus in Human Stool Samples
    Virology
    Diagnostic Accuracy of Four Commercial Triplex Immunochromatographic Tests for Rapid Detection of Rotavirus, Adenovirus, and Norovirus in Human Stool Samples

    Noroviruses (NoV), rotaviruses (RVA), and adenoviruses (AdV) are the main viral agents responsible for acute gastroenteritis (AGE) in humans. We aimed to determine the diagnostic accuracy of four commercial immunochromatographic tests (ICTs) intended for the rapid and simultaneous detection of these three pathogens. Diagnostic accuracy of bioNexia Noro/Rota-Adeno (bioMérieux), Immunoquick NoRotAdeno (Biosynex), Rota+Adeno+Noro combo...

    Jérôme Kaplon, Lucie Théry, Maxime Bidalot, Nadège Grangier, Jean Frappier, Ludwig Serge Aho Glélé, Alexis de Rougemont, Katia Ambert-Balay
  • Simple Phenotypic Tests To Improve Accuracy in Screening Chromosomal and Plasmid-Mediated Colistin Resistance in Gram-Negative Bacilli
    Bacteriology
    Simple Phenotypic Tests To Improve Accuracy in Screening Chromosomal and Plasmid-Mediated Colistin Resistance in Gram-Negative Bacilli

    CLSI and EUCAST recommend that only broth microdilution (BMD) should be used for routine colistin susceptibility testing; however, this technique can be difficult to perform in resource-poor settings. The purpose of this study was to evaluate the accuracy of a colistin agar spot test (COL-AS) and a colistin drop test (COL-DT) compared to BMD. COL-AS and COL-DT were assessed with a collection of 271 Gram-negative bacilli clinical...

    Fernando Pasteran, Diego Danze, Alejandra Menocal, Carla Cabrera, Ignacio Castillo, Ezequiel Albornoz, Celeste Lucero, Melina Rapoport, Paola Ceriana, Alejandra Corso
  • Cefiderocol Antimicrobial Susceptibility Testing against Multidrug-Resistant Gram-Negative Bacilli: a Comparison of Disk Diffusion to Broth Microdilution
    Bacteriology
    Cefiderocol Antimicrobial Susceptibility Testing against Multidrug-Resistant Gram-Negative Bacilli: a Comparison of Disk Diffusion to Broth Microdilution

    Antimicrobial susceptibility testing (AST) of cefiderocol poses challenges because of its unique mechanism of action (i.e., requiring an iron-depleted state) and due to differences in interpretative criteria established by the Clinical and Laboratory Standards Institute (CLSI), U.S. Food and Drug Administration (FDA), and European Committee on Antimicrobial Susceptibility Testing (EUCAST). Our objective was to compare cefiderocol disk...

    C. Paul Morris, Yehudit Bergman, Tsigedera Tekle, John A. Fissel, Pranita D. Tamma, Patricia J. Simner
  • Free
    Closing the Brief Case: <em>Loa loa</em> in a Patient from Nigeria
    The Brief Case
    Closing the Brief Case: Loa loa in a Patient from Nigeria
    Eileen M. Burd, Ahmed Babiker, Jessica K. Fairley, Divya Bhamidipati, Laila E. Woc-Colburn, Blaine A. Mathison
  • Free
    The Brief Case: <em>Loa loa</em> in a Patient from Nigeria
    The Brief Case
    The Brief Case: Loa loa in a Patient from Nigeria
    Eileen M. Burd, Ahmed Babiker, Jessica K. Fairley, Divya Bhamidipati, Laila E. Woc-Colburn, Blaine A. Mathison
  • Evaluation of the Biotoxis qPCR Detection Kit for <span class="named-content genus-species" id="named-content-1">Francisella tularensis</span> Detection in Clinical and Environmental Samples
    Bacteriology
    Evaluation of the Biotoxis qPCR Detection Kit for Francisella tularensis Detection in Clinical and Environmental Samples

    Rapid and reliable detection and identification of Francisella tularensis (a tier 1 select agent) are of primary interest for both medical and biological threat surveillance purposes. The Biotoxis qPCR detection kit is a real-time quantitative PCR (qPCR) assay designed for the detection of Bacillus...

    Aurélie Hennebique, Fabienne Gas, Hélène Batina, Cécilia De Araujo, Karine Bizet, Max Maurin
  • Open Access
    Performance Evaluation of the SAMBA II SARS-CoV-2 Test for Point-of-Care Detection of SARS-CoV-2
    Virology
    Performance Evaluation of the SAMBA II SARS-CoV-2 Test for Point-of-Care Detection of SARS-CoV-2

    Nucleic acid amplification for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in respiratory samples is the standard method for diagnosis. The majority of this testing is centralized and therefore has turnaround times of several days. Point-of-care (POC) testing with rapid turnaround times would allow more effective triage in settings where patient management and infection control decisions need to be...

    Sonny M. Assennato, Allyson V. Ritchie, Cesar Nadala, Neha Goel, Cuijuan Tie, Lourdes M. Nadala, Hongyi Zhang, Rawlings Datir, Ravindra K. Gupta, Martin D. Curran, Helen H. Lee
  • Free
    American Society for Microbiology Provides 2020 Guidelines for Detection and Identification of Group B <em>Streptococcus</em>
    Letter to the Editor
    American Society for Microbiology Provides 2020 Guidelines for Detection and Identification of Group B Streptococcus
    Laura Filkins, Jocelyn R. Hauser, Barbara Robinson-Dunn, Robert Tibbetts, Bobby L. Boyanton, Paula Revell
    and on behalf of the American Society for Microbiology Clinical and Public Health Microbiology Committee, Subcommittee on Laboratory Practices
  • Open Access
    Evaluation of a Fecal Shedding Test To Detect Badger Social Groups Infected with <span class="named-content genus-species" id="named-content-1">Mycobacterium bovis</span>
    Clinical Veterinary Microbiology
    Evaluation of a Fecal Shedding Test To Detect Badger Social Groups Infected with Mycobacterium bovis

    Bovine tuberculosis (bTB) is an economically important disease affecting the cattle industry in England and Wales. bTB, caused by Mycobacterium bovis, also causes disease in the Eurasian badger (Meles meles), a secondary maintenance host. Disease transmission between these two species is...

    Andrew R. J. Murphy, Emma R. Travis, Victoria Hibberd, David Porter, Elizabeth M. H. Wellington
  • Multicenter Performance Evaluation of the Simplexa Bordetella Direct Kit in Nasopharyngeal Swab Specimens
    Bacteriology
    Multicenter Performance Evaluation of the Simplexa Bordetella Direct Kit in Nasopharyngeal Swab Specimens

    Detection of Bordetella pertussis and Bordetella parapertussis using molecular methods is sensitive and specific with a short turnaround time compared to other diagnostic methods. In this multicenter study, we compared the performance of the Simplexa Bordetella Direct kit to those of other molecular...

    Siu-Kei Chow, Sophie Arbefeville, Bobby L. Boyanton, Emily M. Dault, James Dunn, Patricia Ferrieri, Wallace Greene, Morgan A. Pence, Joshua Otiso, Sandra Richter, Ted E. Schutzbank

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Journal of Clinical Microbiology® (JCM) publishes the most current research related to the laboratory diagnosis of human and animal infections and the role of the laboratory in both the management of infectious diseases and the elucidation of the epidemiology of infections.

Editor in Chief: Dr. Alexander J. McAdam

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